Research paper about finish line company Example | Topics and Well Written Essays - 750 words

About finish line company - Research Paper Example It began in 1976 as a partnership between Cohen and Klapper for a ten-year franchise of Athlete’s Foot, an established sports footwear retailer (The Finish Line Inc.). Learning from the franchise experience, the partners opened their own line of sports footwear retail to compete with Athlete’s Foot by offering a wider variety of stocks displayed in bigger stores, as well as offering value brands and affordable lines well-suited in their store locations at less-expensive strip malls. The positioning proved effective as the next ten-years would see growth of the company by opening up more stores with bigger areas while ending the franchise with Athlete’s Foot. To support the growth, two more partners were brought in with sportswear retail experience: Larry Sablonsky and David Fagin (The Finish Line Inc.). The next 20 years saw the growth of the company by overtaking Athlete’s Foot and other competitors in the sports and active wear retail segment as well as becoming a publicly listed company whose shares continue to perform well within its segment. Finish Line’s mission according to the website is to â€Å"connect to young, fashion conscious individuals through a premium brand environment offering the best selection of authentic, sport inspired products† (1). The company offers premium brands that provide dependable quality and leading styles in active wear. Finish Line categorizes its products into footwear and softgoods. As of 2009 annual report, 81% of net sales of Finish Line Inc. came from the footwear category (Lyon and Schneider 3). They carry brands such as Nike, Adidas, Puma, Jordan, Under Armour and New Balance along with sport style brands including Lacoste, Converse, Ed Hardy and Sperry. Softgoods category carries non-footwear products. Recent additions to the company’s line of products are offered through the Paiva store chain offering brands like Tella, McCartney, Brooks, Ellesse, etc., focusing on women

African American vs. Caucasian Americans Essay Example for Free

African American vs. Caucasian Americans Essay At first glance some people might consider this paper to be on the racial side, however it was all written by observations made. There are many differences between African Americans and Caucasians, some people dont see the differences because of ignorance . You must read the paper with an open mind and take none of this to heart. African American and Caucasians function differently in public surroundings. When you see a young African American you usually see them in groups of four of more. However, when one of them gets into a disagreement five to ten more show up in their defense. They are a very close knit group of individuals. I have also noticed that when you see a young African American walking around they are usually singing, talking very loud or running around. Also when they are in groups they are very loud and take over the area that they occupy. On the other hand when you see Caucasians they are rarely in groups of three or more. To top it off when someone in one of their groups gets in trouble the rest of the group is nowhere to be found. Most times when you see young Caucasian people in a group they are for the most part within a normal speaking level. These two groups tend to act differently in the public due to their cultural differences. There are a number of differences between the churches of African Americans and Caucasians. At most typical African American churches there are no true sermons. The African American churches tend to do more entertaining rather than teaching. They also do a great deal of singing and dancing involved in there praising of God. They emphasize fellowship in their churches especially after church when they all gather and close the celebration with a meal together. However at a typical Caucasian church there are a few differences. To start it off when you first walk in you get a program detailing what will be happening through the service. They tend to structure the whole service around a sermon or story. The service every week is very predictable as to what will happen. The Caucasian churches are more there to teach the ways of the lord as they have interpreted it. Although not all the African American and Caucasian churches are along this line a majority of the main stream ones are.

The Effect of Age on Taste Essay -- Senses Aging Essays

The Effect of Age on Taste The sense of taste has to be one of the most important human senses. It gives an individual the ability to recognize consumables that are encountered on a regular basis such as a favorite steak platter or a favorite wine. However, when that individual reaches a particular age the sense of taste deteriorates, which can result in potentially dangerous conditions such as malnourishment or susceptibility to diseases. This problem of taste loss due to aging needs to be studied more because it can effect both the physical and mental health of many elderly people. When elderly individuals try to live life with a weakened ability to recognize certain food flavors or any other consumable item, their dietary needs can be greatly affected. A certain number of foods are not going to taste good enough to satisfy the appetites of the elderly, so they might resort to using unhealthy eating habits. For example, they could lose the motivation to eat certain foods such as vegetables or meats and increase the consumption of foods that are low in nutritional value such as candies or pastries. This shift can result in health problems such as a loss in bone mass, a weakened immune system, weak muscles, and high blood pressure. Elderly citizens need to acquire a specific amount of nutrients in order to maintain a healthy life style. Spence (1989) mentioned that diets which maintain adequate levels of vitamins and minerals and also consist of 50 to 55% carbohydrates, 12 to 15% proteins, and 25 to 35% fats are recommended for persons over the age of 50. In order for the elderly to live up to a healthy diet, they need to consume nutritious foods that will taste good to them. The problem with this situation is how to h... ...ews, 50 (12), 72-75. Miller, J. (1988). Human taste bud density across adult age groups. Journal of Gerontology, 43 (1), 26-30. Schieber, F. (1992). Aging and the senses. In J. E. Birren, R. B. Sloane, & G. D. Cohen (Eds.), Handbook of mental health and aging. San Diego: Academic Press Inc. Schiffman, S. (1977). Food recognition by the elderly. Journal of Gerontology, 32 (5), 586-592. Schiffman, S. (1994). Changes in taste and smell: Drug interactions and food preferences. Nutrition Reviews, 52 (8), 11-14. Schiffman, S. (1997). Taste and smell loss in normal aging and disease. Journal of the American Medical Association, 278 (16), 1357-1362. Spence, A. P. (1989). Biology of human aging. New Jersey: Prentice Hall. Spitzer, M. E. (1986). Taste acuity in institutionalized and non institutionalized elderly men. Psychological Sciences, 43 (3), 71-74.

Delorean Motor Company

DeLorean Motor Company Examining a Business Failure Michael Smith Organizational Leadership 531 September 5, 2011 Examining a Business Failure Stainless Steel. Sleek. Gull-wing doors. Back to the Future. The DMC-12 is one of the most recognizable cars in history. John DeLorean, a former engineer and executive for General Motors, founded the DeLorean Motor Company in October of 1975 (Woron, 1982). DeLorean gained popularity for designing the Pontiac GTO and the Pontiac Firebird.Many thought that John DeLorean was well on his way to being president of General Motors when he left the company in 1973 to start his own automobile company (Woron, 1982). DeLorean needed around $175 million to finance the company, yet only put up around $700,000 of his own money. For the rest, he used over 100 investors to finance his dream, including Johnny Carson and Sammy Davis Jr. (Manning, 2000). He also put over $12 million into a partnership for research and development while the British government pro duced $156 million in grants and loans in return for DeLorean locating the DMC factory in Northern Ireland (Manning, 2000).The DeLorean factory created over 2000 jobs in an area with high unemployment rates. DeLorean had multiple million-dollar homes and paid himself a large salary. When it debuted in 1981, the DMC-12’s sales could not foot the bill. The sports car had a lot of competition and was priced $8,000 higher than the Corvette (Manning, 2000). In February 1982 the British government shut the factory down, John DeLorean began a drug-smuggling scheme to save his company and was busted by the FBI. John DeLorean’s dream was over and left everyone with no return on their investment.Robbins and Judge (2011) define leadership as the ability to influence a group toward the achievement of a vision or set of goals. Trait theories of leadership focus on personal qualities and characteristics (Robbins and Judge, 2011). John DeLorean had every characteristic of an effectiv e leader. He was charismatic, highly successful, courageous, and influential. However, DeLorean had no emotional intelligence and without emotional intelligence a person can have outstanding training, a highly analytical mind, compelling vision, and an endless supply of great ideas, but still not be an effective leader (Robbins and Judge, 2011).DeLorean’s lack of emotional intelligence could have predicted the fall of the DeLorean Motor Company. DeLorean was not self aware, was unable to listen to what followers said, and did not read into the reactions of others. Big executives began leaving the company for a variety of reasons. Many accused DeLorean of being arrogant, disloyal, and distrustful (Woron, 1982). One executive, Robert Dewey, said, â€Å"John would surround himself with fairly intelligent people, but he wanted ‘yes' men. You can get clones to do that. When you challenged him on a point, he felt you were challenging him.You didn't have a dialogue with John. † (Woron, 1982). The fall of the DeLorean Motor Company could have potentially been prevented had John DeLorean listened to his followers. Management theories could have also predicted the failure of the DeLorean Motor Company. The contingency theory suggests that when management makes a decision they take into consideration all aspects of the current situation and act on those aspects that are key to the situation at hand (McNamara, 2011). John DeLorean failed to take all aspects into consideration.DeLorean was starting a new automobile company, yet priced his car higher than the Chevrolet Corvette, Porshe 944, and Mazda RX-7, despite it having less power (Woron, 1982). All of these cars already had a reputation, DeLorean’s DMC-12 did not. He also based the company in Ireland at a time when foreign cars were generally less expensive than those made in the United States. The downfall of the DeLorean Motor Company is largely due to its organizational structure. The comp any’s organizational structure was very centralized, all the power rested at a single point (Mintzberg, Lampel, Quinn, and Ghoshal, 2003).John DeLorean wanted to be that single point of power in his organization, but had over 100 investors. The company also had an innovative strategy, striving to achieve meaningful and unique innovations (Robbins and Judge, 2011). DeLorean chose to build his factory in Northern Ireland to take advantage of low worker wages and for easy access into the European market (Woron, 1982). However, the location of the factory proved to be more an obstacle for DeLorean as he struggled to spend time in Ireland.Delorean’s other innovations included gull-wing doors and stainless steel body panels, but the cars ultimately had to be shipped to U. S. quality control centers to have the door fix the doors and realign body panels. The car ultimately received bad reviews stating the car was heavy, overpriced, and easily showed dirt (Woron, 1982). John D eLorean failed to break-even with the DMC-12 and the factory shut down in 1982. John DeLorean was acquitted of all drug trafficking charges. In 1998 and New York jury ruled that DeLorean’s accounting firm owed investors $46 million, plus $65 million in interest.A man that was once a pioneer had hit rock bottom largely due to excessive spending and his imagination far exceeding his execution. Today, the DeLorean Motor Company is based out Texas with no ties to John DeLorean or his family. The Texas based company acquired all rights to the name and the inventory that was never used (DeLorean Motor Company, 2011). The car is one of the most recognizable in history and has developed a cult following. Had John DeLorean done things differently, his company could have been much more successful. References DeLorean Motor Company. 2011). Retrieved from http://www. delorean. com/q;a. asp Manning, J. (2000). The rise and fall of John DeLorean. Retrieved from http://eightiesclub. tripod. com/id305. htm McNamara, C. (2011). Management help. Retrieved from http://managementhelp. org/management/theories. htm Mintzberg, H. , Lampel, J. , Quinn, J. B. , ; Ghoshal, S. (2003). The strategy process: Concepts, contexts, cases (4th ed. ). Upper Saddle River, NJ: Prentice Hall. Woron, W. (1982). Dreaming the impossible – The DeLorean and its predecessors . Automobile Quarterly, 21(2).

Government Roles in Healthcare Essay

The government which consists of federal, state and local combined has many important roles in the U.S healthcare system. One of the roles in which the government provides is finance. It is estimated that 48% of healthcare was paid for by public dollars in 2008, which included Medicare, Medicaid, state and local health programs, CHIP, and Departments of Defense and Veterans Affairs (Yesalis,Holt,& Politzer,2012). Federal and State governments jointly fund Medicaid, long term mental health services, community health centers and public health programs. The next important role that the government plays in the healthcare system is delivering healthcare to patients. Some examples of healthcare delivery would be the Department of Veterans Affairs which is a federal government operated facility which provides healthcare for veterans. There are hospitals and healthcare facilities which are located on military bases which are run by the federal government that are available for our military service members. There are also federal or state run government healthcare facilities which provide healthcare for uninsured or low income families for little or no cost. The Indian Health Service is another program which is run by the federal government that offers healthcare to American Indians as well. The government also has the role of regulating healthcare. One of the things that the federal government regulates is Medicare and Medicaid providers. State governments are usually more involved when it comes to regulation of healthcare. They regulate things such as: establishing health codes, regulating the insurance industry, and license health care personnel and facilities. The state government works alongside with local health departments to perform other functions as well. Some examples of these are vital statistics, mental health services, and environmental health. References: Yesalis, C., Holt, H., & Politzer, R. (2012). Fundamentals of U.S. Healthcare. Retrieved from http://wow.coursesmart.com/9781428317352/firstsection#

Hegel, Communisme en Nazisme essays

Hegel, Communisme en Nazisme essays 2. Hegels Phnomenologie des Geistes 2 3. Hegels invloed op het communisme en nazisme 5 4. Het gevaar van een naieve benadering 8 Het is vreemd dat in de meeste gevallen Nietzsche wordt aangewezen als de grote beweger van totalitaire politieke stromingen. Deze filosoof is in zijn werk duidelijk beinvloed door Hegel en heeft veel van zijn ideen overgenomen. Geen enkele filosoof kan om het werk van Hegel heen. Zijn werk speelt een belangrijke rol in de ontwikkeling van de politiek in de 19e eeuw. Het lijkt erop dat veel totalitaire politieke stromingen delen van zijn gedachtegoed hebben overgenomen. Het communisme en nazisme lijken bijvoorbeeld gefundeerd op Hegels concept van het Absolute en de Weltgeist. Ik zal in dit werkstuk ingaan de vraag beantwoorden waarom het volgens Hegel noodzakelijk is dat wij niet op een naieve manier een beroep doen op het concept van het Absolute. Ik zal het antwoord op deze vraag geven door Hegels ideen te vergelijken met totalitaire politieke stromingen. Om deze vraag zo goed mogelijk te beantwoorden is het noodzakelijk om Hegels werk ten dele te beschrijven. In de tweede paragraaf zal daarom zijn Phnomenologie des Geistes worden beschreven. Hierna zal ik in de derde paragraaf Hegels invloed op het communisme en nazisme schetsen aan de hand van de in paragraaf twee naar voren gekomen ideen. In de vierde en laatste paragraaf zal ik duidelijk maken wat deze totalitaire regimes missen in hun benadering van het Absolute en in de conclusie zal ik tot een antwoord komen op de hiervoor gestelde vraag. 2. Hegels Phnomenologie des Geistes Georg Wilhelm Friedrich Hegel leefde van 1770 tot 1831. Zijn belangrijkste werk is de Phnomenologie des Geistes (1807) en het is ook het eerste van slechts vier werken. De fenomenologie is de filosofische stroming die uitgaat van de verschijningsvormen van de objecten, dit boek gaat dan ook over de verschijningsvormen van de Ge...

Strategic Project Management

Strategic Project Management Free Online Research Papers Strategic Program Management Worksheet The purpose of this assignment is to begin the process of Problem Based Learning. In this step, you will be looking at one or more realistic situations and using them, in the context of this course, to identify the key concepts involved that you will need to understand in order to solve whatever problems you might encounter in those situations. Complete the table below by identifying at least five concepts that you will study from the text on the rEsource page in order to resolve the situations presented; list and briefly describe them in column A. You have on the resource page a scenario that provides an examples of realistic situation in which these concepts apply. Examine this scenario and in Column B identify specific examples from it which illustrate an application of the concept. The example could be an issue in the scenario which illustrates a concept. Cite in Column C where in the reading you found the concept that the example illustrated. Table for Assignment One A: Concept B: Application of Concept in Scenario C: Citation of Concept in Reading Example from Global Communications Scenario in MBA/500: Building Organizational Commitment, which is developed through the activities of: Justice support Job security Organizational comprehension Trusting employees Example from Global Communications Scenario in MBA/500: Sy states that Global Communication’s competitive edge is drawn from loyal employees, but what will be the effect of laying off employees in the Small Business Group? This contradicts job security as a component of Building Organizational Commitment. Nancy recommends that they tell the truth to the affected employees will accept the explanation, but Nancy is trying to build organizational comprehension (identifying with the organization by keeping employees informed) and re-establish trusting employees, two activities to Build Organizational Commitment. Example from Global Communications Scenario in MBA/500 McShane (2005, ref. pg #?) Project Management Strategy: Expansion Currently, the schools serve about 1000 students, and enrollment increases by roughly 5 percent per year. The Board of Directors believes that number could be higher, that the school could serve even more communities across the United States. Our top priority will be evaluating the first year of our three-year plan. To that end, I’ve asked Nancy to put together a summary of our year-end financial and operating results report, as well as a forecast for the coming year. Although costs are up a few percent, we have negotiated the addition of all of the vacant space in our three buildings at no additional costs. If we are going to expand this school into other states, we will need significantly more funding to acquire additional locations and fund the marketing. We will need to generate at least three to four million in cash for the next two years to give us the funding we need. Our projects have to yield their committed improvements. â€Å"†¦it is time to expand the traditional role of the project manager from an operational to a more strategic perspective. In the modern evolving organization, project managers will be focused on business aspects, and their role will expand from getting the job done to achieving the business results and winning in the market place.† (Gray Larson, 2005, p. 22) â€Å"By watching your overhead you can spend more on business expansion,† (Gray Larson, 2005, p. 95) Four Activities of the Strategic Management Process The typical sequence of activities of the strategic management process is outlined here; a description of each activity then follows: 1. Review and define the organizational mission. 2. Set long-range goals and objectives. 3. Analyze and formulate strategies to reach objectives. 4. Implement strategies through projects. (Gray Larson, 2005, p. 24) Technology to increase efficiency I’ll start with the new â€Å"Life Skills† software. My understanding is that this software would increase the ratio of students to teachers from 3 to 1 to 4 to 1. I see no ratio improvement for next year. Nancy: We are only showing the ratio increase for new teachers and assistants. Most of the older faculty prefers using one-on-one live instruction, and they get excellent results with that. The newer teachers we’re hiring are more open to the computer assisted learning, which increases the ratio. A high level of expertise and technology can be brought to bear on the project (Gray Larson, 2005, p. 68) look at computer technology as the vehicle for work and entertainment. (Gray Larson, 2005, p. 25) Opportunities and threats usually represent external forces for change such as technology, industry structure, and competition. Competitive benchmarking tools are sometimes used here to assess current and future directions. Opportunities and threats are the flip sides of each other. That is, a threat can be perceived as an opportunity, or vice versa. (Gray Larson, 2005, p. 26) Factors such as researching new technology, public image, ethical position, protection of the environment, core competencies, and strategic fit might be important criteria for selecting projects. (Gray Larson, 2005, p. 37) Business development Along with the school’s executive director, the Board has adopted a new strategy that uses business development as the model to increase funding sources and revenues. The three-year strategic program plan includes a number of new projects to help realize this new vision. a new-product development project will likely involve the combined efforts of people from design, marketing, manufacturing, and finance. (Gray Larson, 2005, p. 56) One of the advantages of creating dedicated project teams is that project participants from different functional areas can develop into a highly cohesive work team that is strongly committed to completing the project. (Gray Larson, 2005, p. 62) Project managers have to be able to read and speak the culture they are working in to develop strategies, plans, and responses that are likely to be understood and accepted. (Gray Larson, 2005, p. 77) With the long-term position identified, objectives are set, and strategies are developed to achieve objectives and then translated into actions by implementing projects. Strategy can decide the survival of an organization. Most organizations are successful in formulating strategies for what course(s) they should pursue. (Gray Larson, 2005, p. 24) Profit increase/Stategic placement John (Thomas, Chairperson, Board of Directors) has grown Foundation Schools revenues by nearly 10 percent per year, bringing financials out of the red. As CEO of a large tech company, John has a strong business background, excellent leadership skills, and is well-respected by school faculty and the community. John’s favorite saying is â€Å"Not for profit does not mean ‘for a loss,‘ Nancy and I just returned from a meeting with the Jacobs City School Board and they have agreed to send all of their special needs students to the Foundation Schools starting in September. They have identified 45 students who will be joining us, and they have also agreed to our new rates, which reflect an eight percent increase over the next two years. Nancy: In terms of the financials and operating results, you can see our net income increased because we enrolled more students this year. And as a result of marketing and business development, we expect a major jump in total revenues for next year, a net income increase of nearly two million dollars. Companies have to be disciplined in saying no to potentially profitable projects that are outside the realm of their core mission. This requires other criteria be considered beyond direct financial return. (Gray Larson, 2005, p. 34) Payback formula is Payback period (yrs) _ Estimated Project Cost_Annual savings (Gray Larson, 2005, p. 32) For example, a firm may support projects that do not have high profit margins for other strategic reasons including: To capture larger market share To make it difficult for competitors to enter the market To develop an enabler product, which by its introduction will increase sales in more profitable products To develop core technology that will be used in next generation products To reduce dependency on unreliable suppliers To prevent government intervention and regulation (Gray Larson, 2005, p. 34) Salary initiatives Jennifer: I have increased my ratio to 4 to 1 and find the software is really a great help. But I agree with Nancy, most of the faculty resist it. And there are no real reasons for using it since it does not impact their compensation in any way. Andy: Sounds like we could use a new incentive plan for faculty. I assumed their salary was tied to performance. Jeff: I made the same assumption, when I came on board earlier this year. But the faculty pay system is based on years of service and numbers of degrees, not performance. †¦consider recommending a new performance-driven compensation plan for teachers†¦ However, once a partner, they were virtually guaranteed the position for life and enjoyed significant increases in salary, benefits, and prestige. (Gray Larson, 2005, p.85) Reward criteria- the degree to which rewards such as promotion and salary increases are allocated according to employee performance rather than seniority, favoritism, or other nonperformance factors. (Gray Larson, 2005, p. 73) References Gray Larson. (2005). Project Management: The Managerial Process. Chapter 1. Retrieved from University of Phoenix eBook Collection database. Gray Larson. (2005). Project Management: The Managerial Process. Chapter 2. Retrieved from University of Phoenix eBook Collection database. Gray Larson. (2005). Project Management: The Managerial Process. Chapter 3. Retrieved from University of Phoenix eBook Collection database. Research Papers on Strategic Project ManagementIncorporating Risk and Uncertainty Factor in CapitalThe Project Managment Office SystemAnalysis of Ebay Expanding into AsiaResearch Process Part OneBionic Assembly System: A New Concept of SelfLifes What IfsMarketing of Lifeboy Soap A Unilever ProductTwilight of the UAWStandardized TestingOpen Architechture a white paper

How to Bounce Back When You Make a Mistake at Work

How to Bounce Back When You Make a Mistake at Work The reply-all with a snarky comment, when you meant to forward to a trusted friend. The dropped ball that caused you to miss a major deadline.The â€Å"I’m disappointed in you† talk from your boss.So you’ve made a major mistake at work. Or you’ve gotten a poor review, or maybe you just feel like you’re coasting along, performing way below your ability. Whatever the reason, you feel like you’re just barely holding on. What can you  do when you make a mistake at work?At some point in their career, everyone has a stumbling point. Sometimes mistakes happen due to being overwhelmed, making an oversight, or having a moment of carelessness. It happens to everyone, even the most conscientious employee. So when something happens and you feel like you’re sitting in the corner of shame, remember that you’re not the only one. Even the people who are angry with you have been there (or will be) at some point, so try not to take it too perso nally.The Aftermath of your GaffeAfter a mistake, it can feel like you’re stuck in a kind of purgatory. Am I going to get fired? Have I totally ruined my reputation? And everything, every little bobble or mistake, feels magnified. It’s important not to get stuck under this tidal wave of stress and worry. Once you’ve made a mistake, or been called out for poor performance, the most important thing is to step up.Apologize/acknowledge what happened.You don’t need to wear a sandwich board saying, â€Å"I screwed up,† but letting your boss (and anyone affected by the mistake) know that you understand how you failed is key. If you messed up, a simple â€Å"I’m sorry† goes a long way here, just like it does in all aspects of life. And FYI: â€Å"I’m sorry you feel that way† is not a legit apology here.Own itAccept responsibility for what happened. Resist the urge to throw anyone under the bus here; it won’t lessen your o wn consequences, and will just cause further issues and bad blood. That’s not to say you should take all blame; rather, if it’s a shared mistake or problem, be clear about your part in the mistake, and take your share of the blame. Naming names, or the kindergarten classic â€Å"but he was doing it too!† won’t get you any brownie points right now.Show that it won’t happen againIf it was a lapse on your part, let people know that you’re taking action to make sure it doesn’t happen again. If it was a process that failed, show how you’re changing things so that there’s not a repeat.Look for small winsUnfairly or not, you’re likely going to be under increased scrutiny for some period of time, while things are still recent and raw. In addition to making sure the blunder isn’t repeated, it couldn’t hurt to be an A+ employee for a while: show up early, stay late, put in extra hours to show that you’r e back on it. Take on extra projects to demonstrate your commitment to the job. It’s about rebuilding others’ confidence in you, sure, but it’s just as much about rebuilding your own confidence. Succeeding at things, even small ones, can help you get back into your groove while showing everyone else that you’re ready to move onward and upward.Move onIf it’s not a fatal (e.g. firing) mistake (more on that in a bit), this too shall pass. Odds are, things will get back to normal pretty quickly. And while you can’t erase what happened, or make everyone forget what you did, everyone has a job to do. This incident will get lost in the shuffle of everyday work. You might have a rough few weeks, but at some point you’ll notice that things have gotten back to the routine.Ask Yourself: Why Did This Happen?Once you’ve got the problem in hand and have started your apology tour, you have some space to think more about why this happened. Som etimes mistakes just come out of the blue, in a moment of inattention or poor decision-making. Other times they’re part of a pattern of carelessness, or a lack of caring about the job. So after you’ve started the damage control process, it’s time to figure out why you’re in this situation in the first place.Did I make this mistake/perform poorly because I don’t care about this job anymore?Did I make this mistake/perform poorly because I’m overwhelmed by my job, and need to make adjustments?Did this happen because I don’t have the right skill set, or need to know more about how things work?If you made the mistake or got a poor performance review because you’re just not into your jobIt might be time to get out. It’s not ideal to quit straightaway- it’s much better to start exploring your options and opportunities before you jump ship. But if you’re already performing at a lower level because you’re unh appy or disinterested, that’s a major red flag.If the performance issue was due to you being overwhelmed by your jobTalk to your boss. ASAP. It’s time for a very frank discussion about your priorities, your tasks, and your role. If things don’t change and performance continues to slide, that will be on you, and it will make things even more uncomfortable. Your boss has a strong interest in making sure you perform your best and stay a satisfied employee, so don’t fear the conversation. It might be possible to restructure your daily tasks, or find new ways to do them, so that you’re able to do your job at the level you know you can hit.If the mistakes are happening because you don’t have the right skill setYou need to figure out what you’re lacking, and strategize how to either a) get those skills and knowledge; or b) share responsibilities in a way that works for you and your team. It may be that this is something you can handle on you r own (for example, getting trained on a particular kind of software, or taking online seminars about time management). But it may well be that you need help from someone else in your company, and that’s okay. If you need to sit down with someone to understand processes or tasks, do it. If you need help from your boss prioritizing, ask for it. This goes back to showing that you’ve learned from past mistakes, and are trying to get stronger.What If I’m Fired As a Result?Some mistakes, well, sorry to say that you can’t bounce back so easily and keep your job. Say there was a major money loss, or you happened to do something that was considered unforgiveable by the powers that be. If this turns out to be the case, and you’re let go for cause, your career is not over. Remember before, when I mentioned that you have to work hard to prove yourself and move on? That’s doubly true if you’re fired- and you have to cope with that while also look ing for a new job. So it’s not an easy road, but also not impossible.If you lose your job because of performance issues, you still have options:1. Don’t put off your job search.It can be tempting to lay low for a while, but the longer you wait, you’re delaying the inevitable moment you get back out there. You also run the risk of (unintentionally) reinforcing the idea that you’re unhireable, the longer you stay out of the game. As with a big mistake, accept that it happened, think about how you can do better, and find ways to improve and make yourself a stronger candidate.2. Think hard about what you want to do.Is your field really a good fit for you, after how things ended at your last place? If it was just the company or the role that was the problem, that’s a pretty straightforward fix. But this is a chance to think about what you should really be doing next.3. Get your references in place.Given how things ended, you probably won’t want y our most recent boss to sing your praises (especially if you’re not sure what he/she will say), but you can still get former colleagues from other jobs, or people in your network to act as references.4. Spin it.You lost your job, and that’s going to come up when someone sees an end date on your resume, or asks why you left your last job. The important thing is to turn the narrative into a more positive one. â€Å"I left my last position because it wasn’t a good fit. I’m ready to move on to the next challenge.† It’s a little vague and not ideal, but it’s also not a brutally honest, â€Å"I got fired. Hire me please?† Keep in mind that the reasons you were let go might come up during a background or reference check, so it’s best not to flat-out lie about your reasons for leaving.While you’re looking for a new job, the old one might haunt you somewhat. But again, it’s important to acknowledge, accept, and move on with your life. Everyone loves a good comeback story, and if you work hard to be better than your past mistakes, you can pull yourself up and out of the muck. You can survive, you will survive, and you’ll walk away with some very hard-won insight about yourself and your career.

Heart Disease and Stroke Screening Essay Example | Topics and Well Written Essays - 250 words

Heart Disease and Stroke Screening - Essay Example (Sudano et al., 2010) An example of Screening is where you measure the CRP (C-reactive protein) levels In one’s blood. As a role of the human resistance system, the CRP levels become elevated due to infection. This test is crucial as it helps to determine the risk of one getting stroke or heart diseases. An institute (Lankenau Hospital) in Philadelphia conducts heart illness and stroke with carotid artery ultrasound, ankle brachial index (ABI), abdominal aortic aneurysm (AAA) screening, peak systolic velocity (PSV), heart rhythm electrocardiogram (EKG), mass body index and pressure check in blood at a cost of $50 (Mainlinehealth.org, 2015) The screening tests as per now are very effective and efficient, and I could recommend that everyone does screening test regularly as it very healthy, From study assessment of screening affirms by demonstrating that that individuals with higher cardiovascular illness danger components that did the tests  changed their lifestyle i.e, reduced their cholesterol intake and start to excise. Particular dropout (specific whittling down) inclinations are also affirmed , whereby individuals with more way of life danger components (smoking, higher liquor utilization, overweight) tend to return for subsequent arrangements and follow-up of their conditions. In the long run, regular screening checks help save lives (Sudano et al., 2010) In my opinion there is no need for changes in the screening process as they have and are still providing valid results.Changes may only be nessecessarly in the nearer future when the existing screening test are declared void.The screening programs should be made free since the have a vast range of positive impacts Sudano, I., Flammer, A. J., Periat, D., Enseleit, F., Hermann, M., Wolfrum, M., Ruschitzka, F. (2010). Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease. Circulation.

The Core Benefits of Converse Chucks Essay Example | Topics and Well Written Essays - 500 words

The Core Benefits of Converse Chucks - Essay Example When being produced in the USA, Converse, a company based in the USA, could observe quality control better. The second risk is a loss of control over the Converse product to a certain extent. For example, Indian products might not have the same appearance as an original American product. The first benefit would be the globalization of the product. Instead of selling a product to only Americans, the Converse brand can sell worldwide. The second benefit would be cheaper production in India. Â  marketed its products in approximately 110 countries outside of the United States through subsidiaries, branch offices, independent distributors, and licensees. Non-U.S. sales accounted for 31% of total net sales in 2000. (CVEO Corp.) Â  4. Identify 5 sources of brand equity for Converse and Chuck Taylor AllStars? Basketball shoes are one source of brand equity for Chuck Taylor AllStars. The history of Chuck Taylor AllStars is another source of brand equity. The affordability of Converse is a source of brand equity. The retro/rebel image of Converse is a source of brand equity. Finally, the durability of the brand name is brand equity. Even though Converse went through bankruptcy, the name is known worldwide and in almost every American home. Â  5. Research the current position of Converse in the marketplace. Has it changed strategy since the case was written? If so, how? If not, why do you think they haven’t? Support your answer with an explanation and a source from online research. I believe that the strategy since this case was written is being brought to fruition. Under Nike’s leadership, Converse is growing and thriving.

Western Heritage I Essay Example | Topics and Well Written Essays - 1000 words - 2

Western Heritage I - Essay Example The Binzantine civilization was predominantly Christian in religion, the culture and language was Greek and the administrative authority was the Roman Empire. This civilization was fortressed such that it was protected from attacks from both sea and land. The Islamic civilization started among the Arabs of Arabia. This civilization was founded by Mohammed, a prophet who lived from 570-632 AD. In terms of religious and political order, Muslims used the Koran, a Holy book. According to the Muslims, their faith was the fulfillment of both Judaism and Christianity. Mohammed played a powerful role in bringing together Arabian tribes who constantly warred and diverted their energy to spreading of the Muslim faith. Mohammed was succeeded by Abu-Bakr, a caliph, who ruled according to Koran. The political system was basically theocratical; the government and religion were one and same thing. The Islamic civilization was characterized by common language, common culture and common faith. The Arab dominance eventually began to wane from the 11th Century. Latin Christendom existed in central and Western Europe. Though Islamic and Byzantine civilizations had immense predominance during their time, neither had as much influence in science, technology, philosophy, economics and politics as did Latin Christendom. During the middle age, Latin Christendom was culturally less advanced than the Eastern Civilizations. However, this changed in the twelfth century as Latin civilization began to advance. In medieval Europe, feudalism referred to a social system in which the lords provided military service for the vassals in exchange for land. This system resulted from the failing dominance of the central authority. The period preceding this was characterized by wars, no public revenues and reducing trade activities. Though it provided a replacement for the former system, it was not in itself organized with a basis of logic and foundational

Social Media Research Paper Example | Topics and Well Written Essays - 2000 words

Social Media - Research Paper Example Social media network can be used as an effective tool to promote and market different destinations around the world and to increase awareness in the minds of the people. This paper explains  the importance of  social media network. Effective use of social media networks can help the destination marketing organizations and other hospitality and tourism organizations in attracting the  maximum  number of potential travelers. These social media websites  can be  used as a marketing tool in promoting different destinations. This paper analyzes the different strategies implemented by both DMOs and Non-DMOs through social media websites. It is important to understand that how hospitality and tourism industry is using this social medium to create an impact in the minds of their customers. This paper explains the use of social media networks by DMOs and Non-DMOs and their presence on social media websites. Few examples of DMOs and Non-DMOs are explained in the form of screenshots for the better understanding of their activities, popularity and other marketing campaigns on well known social media networks. Furthermore, the paper concludes on reco mmendations and suggestions that how these DMOs and Non-DMOs can improve their marketing activities on social media networks and how they can attract more people through this widely spread platform. Social Media provides a medium or a platform for social interaction. Social media is facilitated with different tools for technological communication that has changed the shift of traditional communication into a more interactive one (Kietzmann et.al, 2011). Over the years, social media has changed the way of communication between different individuals, organizations and communities. In this age of globalization, social media provides an ease in communication and interaction among different individuals belonging from different parts of the world with different cultural

Stem cell success Term Paper Example | Topics and Well Written Essays - 1750 words

Stem cell success - Term Paper Example This enthusiasm still is not shared by those of the religious right. This faction is opposed to embryonic stem cell research which they claim as immoral and characterize as devaluing human life, much the same as does abortion, drawing a link between the two. This discussion will provide a brief overview of stem cell research and its benefits to society, the debate surrounding the issue and the arguments for continued research. Stem cells are basically the building block cells of a human being which are capable of becoming 210 different types of tissue. Adult stem cells are found in minute numbers within most tissues, but the majority of stem cells can be obtained from the umbilical cord. There are numerous potential sources for stem cells. Embryonic stem cells originate from the inner cell of an early stage embryo. Embryonic germ cells can be collected from fetal tissue at a later stage of development. Adult stem cells can be obtained from mature tissues. â€Å"Even after complete m aturation of an organism, cells need to be replaced. A good example (of adult stem cells) is blood, but this is true for muscle and other connective tissue as well, and may be true for at least some nervous system cells† (Chapman et al, 1999). ... It has been substantiated from animal research that stem cells can be differentiated into cells that will behave appropriately in their transplanted location. For example, the transplantation of stem cells following treatments for cancer has found much success for many years. â€Å"Experiments such as the transplantation of fetal tissue into the brains of Parkinson’s patients indicate that the expectation that stem cell therapies could provide robust treatments for many human diseases is a reasonable one. It is only through controlled scientific research that the true promise will be understood† (Frankel, 1999). The moral dilemma that surrounds the prohibition of aborted fetuses is the idea of abortion itself. The former Bush administration was very conservative leaning and made it very clear that it was opposed to legal abortions, in at least most circumstances, and transferred that ideology to its prohibition of embryonic stem cell research. The concept of scientific study of the next stage of development, the fetus, which resulted from an abortion, is unthinkable. This ideology of that administration reflected the minority opinion which opposes abortion and also reflects the majority opinion that is opposed to aborted fetuses of consenting parents being used for experimentation. This reality has no basis in reason. Why would those who claim to be ‘pro-choice’ want to waste the aborted tissue? For that matter, why would pro-lifers want to witness what they believe is a living being tossed away in vain? At least its ‘life’ could have meant something to humanity in a very real way. Though president Obama reversed the Bush-era restrictions on this scientific research, conservatives continue to fight this battle in court. Last

Market Plan Group Project Assignment Example | Topics and Well Written Essays - 750 words

Market Plan Group Project - Assignment Example The process of how it cools, and how it warms the food should be well explained (Baaghil, 2010). There should be the product itself. The product description should have its functionality, its purpose and its activities. This is a combo product with two main functions. It is a freezer, as well as an oven. One important feature that makes this combination worth having by the consumer is its ability to warm food at a specific set time. Branding should also consider the perception of the product. This is the overall look and feel from the target audience’s view. Consumers will always consider culture’s trends and tastes when it comes to perceptions of new products. This autocookerator, has the advantage since similar products like it are already in the market. It belongs to the new trend of innovation in home automation; specifically, kitchen automation. This also forms part of the brand identity. It belongs to the automation category of home automation appliances (Baaghil, 2010). Brand position and culture: this product will be placed first after work. After work, most people would think of going back home cooking dinner. Even when in fun clubs or short breaks, people will always think of what to have for dinner. It therefore, seeks to be first after work. This information is very important for advertising; when advertising, the most appropriate time to influence consumers’ thoughts is after work. In the consumer market most manufacturers are building ‘smart’ home appliances. This is done based on market research results with the hope that these appliances will enable interaction with the owners, connection to smartphones, interaction with a repairman, interaction with each other, and even negotiation with the power company over rates. The manufacturers are focused on a more an efficient way of dealing with home appliances. This already development

Stem cell success Term Paper Example | Topics and Well Written Essays - 1750 words

Stem cell success - Term Paper Example This enthusiasm still is not shared by those of the religious right. This faction is opposed to embryonic stem cell research which they claim as immoral and characterize as devaluing human life, much the same as does abortion, drawing a link between the two. This discussion will provide a brief overview of stem cell research and its benefits to society, the debate surrounding the issue and the arguments for continued research. Stem cells are basically the building block cells of a human being which are capable of becoming 210 different types of tissue. Adult stem cells are found in minute numbers within most tissues, but the majority of stem cells can be obtained from the umbilical cord. There are numerous potential sources for stem cells. Embryonic stem cells originate from the inner cell of an early stage embryo. Embryonic germ cells can be collected from fetal tissue at a later stage of development. Adult stem cells can be obtained from mature tissues. â€Å"Even after complete m aturation of an organism, cells need to be replaced. A good example (of adult stem cells) is blood, but this is true for muscle and other connective tissue as well, and may be true for at least some nervous system cells† (Chapman et al, 1999). ... It has been substantiated from animal research that stem cells can be differentiated into cells that will behave appropriately in their transplanted location. For example, the transplantation of stem cells following treatments for cancer has found much success for many years. â€Å"Experiments such as the transplantation of fetal tissue into the brains of Parkinson’s patients indicate that the expectation that stem cell therapies could provide robust treatments for many human diseases is a reasonable one. It is only through controlled scientific research that the true promise will be understood† (Frankel, 1999). The moral dilemma that surrounds the prohibition of aborted fetuses is the idea of abortion itself. The former Bush administration was very conservative leaning and made it very clear that it was opposed to legal abortions, in at least most circumstances, and transferred that ideology to its prohibition of embryonic stem cell research. The concept of scientific study of the next stage of development, the fetus, which resulted from an abortion, is unthinkable. This ideology of that administration reflected the minority opinion which opposes abortion and also reflects the majority opinion that is opposed to aborted fetuses of consenting parents being used for experimentation. This reality has no basis in reason. Why would those who claim to be ‘pro-choice’ want to waste the aborted tissue? For that matter, why would pro-lifers want to witness what they believe is a living being tossed away in vain? At least its ‘life’ could have meant something to humanity in a very real way. Though president Obama reversed the Bush-era restrictions on this scientific research, conservatives continue to fight this battle in court. Last

In the United Kingdom the big four supermarkets of Tesco, Asda, Essay

In the United Kingdom the big four supermarkets of Tesco, Asda, Sainsbury's and Wm Morrison have gained a steadily increasing - Essay Example In recent time some of the retail giants of United Kingdom like Sainsbury, Asda, Morrisons and Tesco have been accused of swindling the suppliers by paying them the bottom prices or finding some other way by which they can pressurise the suppliers to pay the cost of the unsold or perished goods. There are also other ways by which the suppliers are exploited that includes paying lower than the agreed price after the delivery of the order, delaying to pay them, make changes in the order at the last moment, making the suppliers to bear the cost, forcing the supplier to use certain specific expensive hauliers for delivering their goods and often ruining the supplier due to lack of cash flow. The supermarket retailers even pressurised the suppliers to pay for the shoplifted goods and making their profits to rise high, when they are expected to be lower. The study focuses on this issue. Supermarket competition Relentless rise in the supermarkets has given rise to the concern regarding thei r holdings over the suppliers and the customers. A research conducted by TNS Worldpanel, the market research group has concluded that the big four retail giants of UK Morrisons, Sainsbury's, Asda and Tesco holds almost three quarter of the grocery market that amounts to about 74.4%. Tesco is the leading supermarket that holds the biggest share. The report suggests that for every ?8 the consumer spends ?1 goes towards the business of Tesco. In 2004 it has been recorded that the retail sector of UK amounts to almost ?246bn, which is more than the amount if the economies of Ireland and Switzerland are combined together. This implies that the retail sector offers quite a significant amount (BBC News, 2006). (Source: BBC News, 2006) According to the reports of the All Party Parliamentary Small Shops Group, almost half of 278,630 shops in UK are managed and owned by a sole trader. These small local stores are losing their market because of the growth of the supermarkets that are gradually moving towards the convenience store format. As per the report of Association of Convenience Store for the last twelve months till June of 2005, 2000 independent convenience stores closed their operations owning to the growing competition of the supermarkets. The Office of fair Trading (OFT) has been investigating the two main issues firstly the competition that surrounds the worries regarding the competition in the supermarkets and abusing relationship between the supermarket and the suppliers. The OFT has claimed that there is no restriction on the grocery market, which prompts a widespread scorn from the action group and the local shops. OFT further states that there is no need of incorporating any type of reform in the ways the super markets are operating; though there are claims regarding application of bullying tactics by the four big supermarkets. According to the recent declaration of OFT there are significant indications regarding increase in the purchasing power of the cu stomer of the supermarket (BBC News, 2006). Area of Concern The corner and local shop areas are becoming the potential places for the growth of the supermarkets. The four big supermarkets face certain restrictive measures that pave the pathway for expanding their operations by following the convenient store format. This also helps the supermarkets to target the customers who are cash rich

College Education Essay Example for Free

College Education Essay In his essay entitled â€Å"How to Get a College Education†, Jeffrey Hart described the negative effect of Allan Bloom’s book The Closing of the American Mind on his Dartmouth freshman composition course students. These students, Ivy-leaguers and top test scorers, disliked the book’s criticism of their mentality but at the behest of Hart’s impromptu oral quizzing, could not adequately discuss historical figures and events. Although Hart’s freshman class realized the gaps in their education, Hart asks what a real college education is, deplores the advent of specialization, and discusses what does or does not constitute real education. Hart’s concern with education lies with the end result: to produce a citizen. But while Hart gives excellent examples for what subjects he thinks constitute a real education in light of telos, a goal, he implies, rather than specifies, that such an education must cater to proactive, independent thought over ideologically based curriculum and courses. It is through well-rounded, balanced independent thought, Hart argues, that a citizen who can â€Å"recreate his civilization† be made. In the first example, Hart names a curriculum engaged in â€Å"so-called post modernist thought† as something to avoid. It is one of the three â€Å"intellectual fads†, in which the use of the word â€Å"fad† describes a fashionable conduct as enthusiastically followed by a group. This way, Hart indirectly refers to post modernist thought as ideological and lacking in independent thought. The second â€Å"fad† refers to Affirmative Action, which Hart describes as an â€Å"ethos† or â€Å"mentality†. â€Å"Ethos† describes the disposition of a culture or a group, and â€Å"mentality† refers to the set of a person or a group’s mind; and both words conjure a certain blindness that Affirmative Action is supposed to fight. Again, Hart reflects on the dearth of nuance and consideration in such courses. Thirdly, Hart directly mentions ideology when he writes about Marxism, victimology, and identity politics, in which â€Å"scholarly pursuit† is put aside in deference to â€Å"’Studies’ programs†. Hart calls many of these courses â€Å"nonsense† and â€Å"distraction†, but fails to directly write that the single underlying theme of such courses is that because they operate under an ideology, they do not foster free thinking and independent rationality. Hart underlines his position for independent rationality by going on to discuss courses and curricula that he thinks support the end goal of citizenship. Rationality is implied when Hart takes on the subject of requiring a student to know and understanding themes in civilization, a task that maneuvers beyond mere adherence to ideological standards. The student must know his civilization: â€Å".. its important areas of thought, its philosophical and religious controversies, the outline of its history and its major works. The citizen need not know quantum physics, but he should know that it is there and what it means. Once the citizen knows the shape, the narrative, of his civilization, he is able to locate new things — and other civilizations — in relation to it. † By referring to controversies, major works, and narrative, Hart’s stance on education is of well-roundedness, independent thought, and being comfortable on differing sides of issues—a stance not suitable to the ideologically minded. Hart makes connections to Athens and Jerusalem in order to outline how a student may develop her college education. Both Athens and Jerusalem were and are centers of independent thought. Athens refers to the ancient Greek capital in which rational thought, philosophy, and democracy were birthed; it was the birthplace of philosophers such as Socrates, Plato, and Aristotle: Of things useful and necessary only those that are free should be taught, and the young should partake in nothing of a vulgar, mechanical sort or that will render body, soul, or thought unfit for virtue. (Philips 154). Jerusalem, since the reign of Solomon, has been the spiritual capital of three major religions in the world today. Independent thought emerges out of Jerusalem in the guise of Abraham who sought argument with God, and Jesus, who argued and fought with the spiritual leaders priests and scribes, or Pharisees and Sadducees—of his day (Columbia). A student, dynamically engaged with both scientifically rational and enlighteningly spiritual sides, can succeed in mastering themes of his or her civilization with independence of thought rather than subsisting on an ideological track. Such a student would be able to carve for him or herself a true education with a goal of not being simply educated, but a goal of becoming an involved, active citizen of society, and of a civilization. Hart discusses China as a final example to his essay. Hart reminds us that one could consider China, who has lacked the dynamic interaction between science and spirituality, and who is world renowned for its collectivist culture, one in which independent thought is frowned upon. Again, Hart does not directly mention this, but references it with mentioning China with its â€Å"symbols†: Great Wall and Forbidden City. REFERENCES Jerusalem. The Columbia Encyclopedia, Sixth Edition. 2007. Philips, Peter L. The Politics of Aristotle. University of North Carolina Press, 1997

Degenerative Joint Disease Or Osteo Arthritis Nursing Essay

Degenerative Joint Disease Or Osteo Arthritis Nursing Essay Osteoarthritis is the most common cause of disability in the United States. Osteoarthritis affects an estimated 27 million Americans. This painful condition develops when there is a breakdown of cartilage in the joints (Shaw, 2012, p.1). Osteoarthritis can occur with age, or it can be caused by a joint injury or stress on the joints from a specific job, sport or being overweight. Over time, some people experience extreme inflammation and permanent damage to the joint. The joint may even need to be surgically replaced. The chance of developing the disease increases with age. Most people over age 60 have osteoarthritis to some degree, but its severity varies. Even people in their 20s and 30s can get osteoarthritis. In people over 50, more women than men get osteoarthritis (Gazella, 2009). Bone ends are covered with a layer of cartilage and lubricated by a synovial fluid to provide less friction and a smooth surface for the bones to move over each other. The whole joint is enclosed by the synovial sac (Gazella, 2009). In osteoarthritis, the cartilage becomes thinner and rougher while the bone underneath thickens. The ends of the bones start to rub against each other which causes pain and even more damage. The bones try to repair themselves, but this is not very successful, so it results in a more uneven surface of spurs and cracks. The synovium also produces extra fluid, which results in swelling, and there are changes to the ligaments, which cause movement restriction. Muscles may also become weaker Progression is slow and many patients diagnosed with OA will not suffer a great degree of deterioration (Gazella, 2009). The most common other form of arthritis is rheumatoid arthritis (RA), which has a different pattern of signs and symptoms, although some of the symptoms may overlap. Symptoms of OA can also vary, with flares and remission, which can make diagnosis more difficult. Other factors such as the cold and damp weather often can increase pain. One complication which can occur is calcification, which is when deposits of calcium crystals form in the cartilage to cause further swelling and the joint can become hot and red. Pain and stiffness in the joints are the most common symptom. The pain is often worse after exercise and when you put weight or pressure on the joint. Your joints may ache, or the pain may feel burning or sharp. For some people, the pain may come and go. Constant pain or pain while you sleep may be a sign that your arthritis is getting worse. When you have arthritis, getting up in the morning can be hard. Your joints may feel stiff and creaky for a short period of time, until you get moving. You may also get stiff from sitting. The muscles around the joint may get weaker. This happens a lot with arthritis in the knee. Arthritis can cause swelling in joints, making them feel tender and sore. Joints can start to look like they are the wrong shape, especially as arthritis gets worse. As it gets worse, you may not be able to fully bend, flex, or extend your joints. Or you may not be able to use them at all. Your joints may make crunching, creaking sounds. This creaking may also occur in a normal joint. But in most cases, it doesnt hurt and doesnt mean that there is anything wrong with the joint. The phrase morning stiffness refers to the pain and stiffness you may feel when you first wake up in the morning. Stiffness usually lasts for 30 minutes or less. It can be improved by mild activity that warms up the joint (Shaw, 2012). There are several factors that can increase the risk for developing osteoarthritis, including heredity, obesity, injury, or overuse of certain joints. People born with abnormalities are more likely to develop osteoarthritis. Some people have an inherited defect in one of the genes responsible for making collagen a major component of cartilage; this causes defective cartilage, which leads to more rapid deterioration of joints (Gazella, 2009). Obesity increases the risk of osteoarthritis. Maintaing ideal weight or losing excess weight may help prevent osteoarthritis, or decrease the rate of progression once osteoarthritis is established. Injuries contribute to the development of osteoarthritis. For example, athletes who have knee-related injuries may be at higher risk of developing osteoarthritis of the knee. In addition, people who have had a severe back injury may be predisposed to develop osteoarthritis of the spine. People who have had a broken bone extending into the joint margin are prone to develop osteoarthritis in that joint (Osteoarthritis, 2009). Overuse of certain joints increases the risk of developing osteoarthritis. Osteoarthritis is not associated with fever, weight loss, or anemia. As of now there is no known cure for osteoarthritis, but treatments can help to reduce pain and maintain joint movement. Acetaminophen (Tylenol) can relieve pain, but doesnt reduce inflammation. It has been shown to be effective for people with osteoarthritis who have mild pain to moderate pain. Taking more than the recommended dose can cause liver damage (Mayo Clinic, 2012). Non-steroidal anti-inflammatory drugs (NSAIDs reduce inflammation and reduce pain. Over-the-counter NSAIDs can cause stomach upset, ringing in your ears, cardiovascular problems, bleeding problems, and liver and kidney damage. Narcotics typically contain ingredients similar to codeine and may provide relief from more severe osteoarthritis pain. These stronger medications carry a risk of dependence, though that risk is thought to be small in people who have severe pain. Side effects include nausea, constipation, and sleepiness (Researchers from National Research Center Describe Findings in Osteoarthritis, 2012). Working with a physical therapist can help. The physical therapist can work with you to create an individualized exercise regimen that will strengthen the muscles around your joint, increase the range of motion in your joint and reduce your pain. Find ways to go about your day without stressing your joints. Consider trying splints, braces, shoe inserts or other medical devices that can help reduce your pain. These devices can immobilize or support your joint to help you keep pressure off it (Gazelle, 2009). The Arthritis Foundation and some medical centers have classes for people with osteoarthritis or chronic pain. These classes teach skills that help manage osteoarthritis pain. Injections of corticosteroid medications may relieve pain in the joint. During this procedure the doctor numbs the area around the joint, and then inserts a needle in the space within the joint and injects medication. The number of cortisone shots you can receive each year is limited, because the medication can cause joint damage (Mayo Clinic, 2012). Injections of hyaluronic acid derivatives may offer pain relief by providing some cushioning in your knee. These treatments are made of rooster combs and are similar to a component normally found in your joint fluid (Mayo Clinic, 2012). In joint replacement surgery (arthoplasty), the surgeon removes the damaged joint surfaces and replaces them with plastic and metal devices called prostheses. The hip and knee joints are the most commonly replaced joints. Surgical risks include infections and blood clots. Artificial joints can wear out or come loose and may need to eventually be replaced (Shaw,2012). Medications and other treatments are key to managing pain and disability, but another major component to treatment is your own attitude. Your ability to cope despite pain and disability caused by osteoarthritis often determines how much of an impact osteoarthritis will have on your everyday life. Make a plan with your doctor for managing your arthritis. This will help make you feel that youre in charge of your disease rather than vice versa. Studies show that people who take control of their treatment and actively manage their arthritis experience less pain and function better (Mayo Clinic, 2012). It is also important that you know your limits. Rest when you think it might be needed. Arthritis can make a person feel fatigued and makes that person prone to muscle weakness, a deep exhaustion that makes everything you do a great effort. Resting or taking a short nap that doesnt interfere with nighttime sleep may help a great deal.

Computational Complexity and Philosophical Dualism :: Dualism Essays

Computational Complexity and Philosophical Dualism ABSTRACT: I examine some recent controversies involving the possibility of mechanical simulation of mathematical intuition. The first part is concerned with a presentation of the Lucas-Penrose position and recapitulates some basic logical conceptual machinery (GÃ ¶del's proof, Hilbert's Tenth Problem and Turing's Halting Problem). The second part is devoted to a presentation of the main outlines of Complexity Theory as well as to the introduction of Bremermann's notion of transcomputability and fundamental limit. The third part attempts to draw a connection/relationship between Complexity Theory and undecidability focusing on a new revised version of the Lucas-Penrose position in light of physical a priori limitations of computing machines. Finally, the last part derives some epistemological/philosophical implications of the relationship between GÃ ¶del's incompleteness theorem and Complexity Theory for the mind/brain problem in Artificial Intelligence and discusses the compatibili ty of functionalism with a materialist theory of the mind. This paper purports to re-examine the Lucas-Penrose argument against Artificial Intelligence in the light of Complexity Theory. Arguments against strong AI based on some philosophical consequences derived from an interpretation of GÃ ¶del's proof have been around for many years since their initial formulation by Lucas (1961) and their recent revival by Penrose (1989,1994). For one thing, Penrose is right in sustaining that mental activity cannot be modeled as a Turing Machine. However, such a view does not have to follow from the uncomputable nature of some human cognitive capabilities such as mathematical intuition. In what follows I intend to show that even if mathematical intuition were mechanizable (as part of a conception of mental activity understood as the realization of an algorithm) the Turing Machine model of the human mind becomes self-refuting. Our contention will start from the notion of transcomputability. Such a notion will allow us to draw a pathway between formal and physical limitations of symbol-based artificial intelligence by bridging up computational complexity and undecidability. Furthermore, linking complexity and undecidability will reveal that functionalism is incompatible with a materialist theory of the mind and that adherents of functionalism have systematically overlooked implementational issues. 1 - The Lucas-Penrose argument — Lucas-Penrose argument runs as follows: GÃ ¶del's incompleteness theorem shows that computational systems are limited in a way that humans are not. In any consistent formal system powerful enough to do a certain sort of arithmetic there will be a true sentence — a GÃ ¶del sentence (G) — that the system cannot prove.

Promotion and Pricing Strategies

Week 8 e-Activity Use the Internet or the Strayer Library to research a recent situation that has caused a business, not-for-profit organization, or government agency to suffer from bad publicity. Be prepared to discuss. â€Å"Promotion and Pricing Strategies† Please respond to the following: From the e-Activity, evaluate the situation of the organization you researched. Create a program outlining steps the organization might take to build better public relations. Ensure their search engines are being far to the consumer’s wants and needs.Rewrite its policy and procedures for marketing to support the consumers not just the brands they have a market share in. Employ outside audit agency to ensure coding is not limiting, collecting, or distributing user information even if it is for marketing. Take fault where fault should be taken, after all how can you say you don’t put other websites before others yet have a marketing team where you can buy key words that help m ove you up in your rankings. Source: http://www. computerworld. com/s/article/9230149/Bad_press_may_affect_Google_more_than_FTC_s_22. M_fine http://www. reuters. com/article/2012/10/12/us-google-ftc-antitrust-idUSBRE89B16G20121012 http://www. computerworld. com/s/article/9234096/Google_CEO_Page_said_to_meet_with_FTC http://www. nytimes. com/2012/10/13/technology/ftc-staff-prepares-antitrust-case-against-google-over-search. html? pagewanted=all From Case Study 13. 3, analyze the airline’s marketing strategy; its use of social media and free publicity. Speculate whether or not this strategy will allow the airline to reach its target market. Provide a rationale with your response.Pet travel is becoming part of the norm for travelers. Interesting is that hotel have started to adapt a more pet friend attitude to pets yet it took the airline industry a little longer to recognize this new segmented market. As a pet lover my dog goes with me on vacation so often I find it a challenge to find a flight to get my dog to go with me but easy to find places to rent. There are a lot of regulations for most companies that offer this service such as pet weight, bread, container of travel, and even destination. And I found all this true for Pet Airways as well.They seem to have a great concept but if you look at other airlines such as JetPaws better known as jetBlue not only do you get rewards points but there are more destinations and options for your pet. There are concerns with Pet Airways such as I’d rather my pet be on the same flight as me but as good as it sounds your pet will be on their own plan with other pets. With price ranging from 299 on up there are cheaper and faster options out there. Looking at the public relations side of the house I found several articles that spoke about writers visiting the Pet Airways but not given information or even a look at the pet holding area.There is one thing for sure those with pets who are taking this much care to make sure their pet is with them are more than likely going to want to check the entire facility out before checking their pets in. Just as the airline would do if you want your pet to fly with them. So this is where I would start: 8) Advertise in the top 3 animal pet stores (PetSmart, PetCo, and Pet Supplies Plus). 9) Take their youtube video (http://www. youtube. com/watch? v=sc2lvz1LGTc) and send out emails to customers via the top animal pet stores, local veterinarians in markets they service. Source: http://seniortravel. about. com/od/airtravel/a/PetAirways. htm

Heat Transfer Lab Report

UNSTEADY STATE HEAT TRANSFERHeat transfer processes are prominent in engineering due to several applications in industry and environment. Heat transfer is central to the performance of propulsion systems, design of conventional space and water heating systems, cooling of electronic equipment, and many manufacturing processes (Campos 3). Unsteady state conduction is the class of heat transfer in which the temperature of the conducting medium varies with time and position.This occurs frequently in industrial processes, especially food preservation and sterilization, where the temperature of the food or of the heating or cooling medium constantly changes (Farid2). The work reported here involves the investigation of unsteady state heat transfer in two cylindrical rods and the conformity of experimental results to different methods of theoretical analysis. Aluminum and Plexiglas cylinders were used. Thermocouples were placed at different radial and axial positions, and the cylinders, whi ch were in thermal equilibrium with an ice bath, were placed in a warm water bath at 370C.Temperature profiles were obtained using a data acquisition system on a computer. Theory The applicable form of the heat transfer equation for conduction in solids is given by (Welty1): If the thermal conductivity is constant and the conducting medium contains no heat sources, Equation 1 reduces to Fourier’s second law of heat conduction (Welty1).Equation 2 can be written in cylindrical coordinates as   (3) Assuming that no heat transfer occurs in the axial position, and temperature varies with radial position and time only, (4) Equation 3 therefore becomes (Welty1) (5) Nomenclature for all equations is shown in the appendices.For a cylindrical rod immersed in a higher temperature fluid, heat transfer occurs by convection from the body of fluid to the surface of the rod, and by conduction from the rod’s surface to its center. If conduction through the rod occurs much faster than convection from the fluid, convection is the rate-limiting heat transfer mechanism, and the temperature within the solid will vary with time only. This condition, in which the external resistance is large relative to the overall resistance, is the primary characteristic of a â€Å"lumped† system.The Biot number, (Bi = hV/kA), is a ratio of the internal (conductive) resistance to heat transfer, to the external (convective) resistance to heat transfer. A general rule of thumb is that a body can be assumed to be lumped if Bi < 0. 1 (Welty1). For lumped bodies, the temperature variation with time is described by Equation 6 (Welty1) For cases in which the internal and external resistances are significant, Equation 5 must be solved numerically or graphically to determine the temperature variation with position and time.Graphical solutions (Heisler charts) are shown in Welty1 for different shapes and geometries. To use the Heisler charts, three dimensionless ratios must be known, a nd a fourth will be read on the appropriate axis. These dimensionless ratios are: Y, unaccomplished temperature change=T? -TT? -T0 (7) X, relative time=? tx12 (8) n, relative position=xx1 (9) m, relative resistance=khx1 (10)DISCUSSIONBefore the data was analyzed, the thermocouples were calibrated and the voltage readings were converted to temperature. To achieve this, the final value from each thermocouple was set to be equal to the warm water bath temperature (370C), and the initial reading was set equal to the ice water bath temperature. Thus, for each thermocouple an equation was obtained using the two points to convert voltage readings to temperature. An example of the calibration for one of the thermocouples is shown in AppendixII. LUMPED ANALYSISTo determine if a lumped-parameter analysis could be applied, the Biot numbers for the systems were calculated (shown in Table 1). Table 1: Biot numbers for the aluminum and Plexiglas cylinders. | Bi| Aluminum| 0. 07| Plexiglas| 81| Si nce the Bi value of the aluminum system is less than 0. 1, convection from the water to the surface of the cylinder is the rate limiting heat transfer mechanism. Thus, a lumped-parameter analysis can be safely applied. The Plexiglas system, on the other hand, has a Bi >> 0. 1, and the rate limiting mechanism is conduction in the cylinder.The temperature-time plot gotten by applying a lumped-parameter analysis (Equation 6) to the Aluminum cylinder was compared to the plot obtained from the thermocouple located closest to center of the cylinder. This thermocouple is chosen for comparison because it is located farthest from the heating source and will have a temperature history that differs most from an ideal lumped system. With this thermocouple, we should therefore obtain the maximum error associated with applying a lumped-parameter analysis to the system.Figure 1: Temperature history plot for the aluminum cylinder. The thermocouple is located 0. 25 in away from the center. A lumped parameter analysis is also shown in Figure 2 for the Plexiglas cylinder to illustrate the error encountered by applying Equation 6 to â€Å"un-lumped† systems. Figure 2: Temperature history plot for the Plexiglas cylinder.COMPARING TEMPERATURE HISTORY AT DIFFERENT RADIAL POSITIONSBased on their Biot numbers, it was expected that the temperature history plots at different radii for the aluminum cylinder should follow a similar path, while those for the Plexiglas cylinder shouldn’t. Figure 3: Experimental temperature for the aluminum cylinder history at various radial positions. Figure 4: Experimental temperature for the Plexiglas cylinder history at various radial positions. Figures 3 shows that the temperature curves are all the same at different radii in the aluminum cylinder.This is attributed to the fact discussed earlier that the aluminum cylinder behaves as a lumped system, that is, there is negligible resistance to internal heat transfer (conduction). Figure 4, o n the other hand, shows differences in the temperature history plots at different radii in the Plexiglas cylinder, confirming that conduction through the cylinder is the rate limiting heat transfer mechanism.GRAPHICAL SOLUTION –HEISLER CHARTSFor systems that cannot be accurately modeled by lumped-parameter solutions, such as the Plexiglas cylinder, we must resort to other analytic methods.Graphical solutions in Heisler charts (Welty1) were used to estimate the temperature history at three thermocouples. These plots are compared with the experimental plots in Figures 5 – 7. Figure 5: Experimental and graphical-solution temperature history plot. The thermocouple is located at a radius of 1. 25 in away from the center. Figure 6: Experimental and graphical-solution temperature history plot. The thermocouple is located at a radius of 0. 50 in away from the center. Figure 7: Experimental and graphical-solution temperature history plot. The thermocouple is located at the cent erline of the cylinder.The percent differences show that predicting the temperature history using Heisler charts produces much error. This method was open to mistakes for the following reasons: 1. Curves on the charts are drawn for integer values of relative time, position and resistance. Therefore, reading and approximation errors result when decimals to be read are not shown on the axes. 2.Some areas of the Heisler charts are so crowded with lines that reading a value with accuracy is nearly impossible. 3. When producing the charts, Heisler did calculations for some set of numbers and then linearly connected the points on a logarithmic-linear modified scale. Dimensionless ratios obtained from the charts are thus slightly different from their real values (Dilsiz4).NUMERICAL ANALYSIS – MATLABEquation 5 was solved numerically using MATLAB. The code used is provided in Appendix IV. The solutions were extracted to Excel and plotted (Figures 8 and 9).The temperature plots at diff erent radii for the aluminum cylinder are superimposed and therefore indistinguishable. This further demonstrates the fact that the temperatures at all points in the aluminum system were identical. Figure 9, on the other hand, shows that the Plexiglas had varying temperatures at different points. Figure 8: Numerical Solution from for the aluminum cylinder. Results were found using MATLAB and plotted in Excel. Figure 9: Numerical Solution from for the Plexiglas cylinder. Results were found using MATLAB and plotted in Excel. The results obtained from the numerical analysis were compared with experimental data.Table 4 shows the average percent differences between their values. The percent differences for the Plexiglas cylinder are significantly lower than those obtained when using the Heisler charts (see Table 3). This suggests that the numerical analysis using a partial differential equation solver is a more reliable method of analyzing the data for the Plexiglas cylinder. Table 4: Av erage percent differences between experimental results and the numerical analysis solution. Radius (in)| Average % difference| | Aluminum| Plexiglas| 0| -| 7. 54| 0. 25| 3. 68| 5. 81| 0. 5| -| 5. 75| . 75| 2. 99| -| 1| 3. 35| 6. 34| 1. 25| 2. 27| 4. 92| | | | Average| 3. 0725| 6. 072|CONCLUSIONThe rate limiting heat transfer mechanism for the aluminum and Plexiglas cylinders were convection and conduction, respectively. It was found that the temperature history for the aluminum cylinder conformed to a lumped-parameter analysis while that for the Plexiglas cylinder didn’t. This was expected based on the Biot numbers calculated for the two systems. Temperature profiles obtained from Heisler charts produced much error, and deviated significantly from experimental data.For the Plexiglas cylinder, the numerical analysis using MATLAB, although tedious, provided the least error when compared to experimental results. The temperature histories at different radial positions were compar ed: the temperature-time curves for the aluminum cylinder overlapped, that is, the temperatures were the same at different radial positions. On the other hand, there were significant differences in the temperature-time curves for the Plexiglas cylinder. This is attributed to the fact that the aluminum rod was lumped, while the Plexiglas wasn’t.SOURCES OF ERRORIt was assumed that no heat was transferred through the ends of the cylinders. This may have induced some error in the analysis. If there was indeed significant heat transferred through the ends, two thermocouples placed at the same radius will report slightly different temperatures, with the one closer to the edge being heated faster. As discussed earlier, error is introduced when reading the Heisler charts. These errors were considered minor, and were not substantial enough to affect the major conclusions drawn from the analysis.SAFETY CONSIDERATIONSThe proximity of water baths to electrical equipment presented an elec trical hazard.It was important to make sure not to spill water when transferring the cylindrical rods between baths. We also made sure to move any movable electrical equipment as far as possible from the immediate area. The baths used weren’t hot enough to cause scalds upon contact with the skin. Safety glasses and closed-toed shoes were worn throughout the duration of the experiment.REFERENCES1. Welty, James R. , Charles E. Wicks, Robert Wilson, and Gregory L. Rorrer. Fundamentals of Momentum, Heat, and Mass Transfer. New York: Wiley, 2001. Print.2. Farid, Mohammed M. Sterilization of Food in Retort Pouches. New York, NY: Springer, 2006. Print.3. Campos, Marco, Estaner Claro Romao, and Luiz Moura. â€Å"Analysis of Unsteady State Heat Transfer in the Hollow Cylinder Using the Finite Volume Method with a Half Control Volume. † Applied Mathematical Sciences 6. 39 (2011): 1925-931. Print.4. Dilsiz, Resul, and Onur Y. Devres. â€Å"Graphical Solution of the Transient Hea t Transfer Problem. † AIP Conference Proceedings 1048. 855 (2008).

Buyer Behavior & Integrated Marketing

The problems on which this assignment focuses on is how can an organization understand and influence the demands and needs of a consumer by using consumer decision making model and the a decision sequence model which helps an organization define a set sequence in order to plan for its marketing and promotional strategy. The company that has been researched upon in the research paper is Automobili Lamborghini S. p. A that has recently launched its new SUV in the market which also happens to be the first SUV car from the company.The car is known is Lamborghini SUV and there are a lot of things that need to be taken care of when introducing and marketing the car in automobile arena. A consumer decision model will help the company in order to see how a particular group of consumers decides for a particular commodity. What are their preferences, their expectations, how can they be attracted, what is their taste, how well do they memorize a certain product, their loyalties to a particular brand, their interpretation from a product or marketing strategy and the knowledge that they possess.A consumer consciously or unconsciously using all these factors when going to buy a product thus in the case of Lamborghini SUV the consumer will again question himself on the above mentioned grounds (MacKenzie 1986). As given in the research done on the company, the main problems that the company tends to identify from the consumer behavior are; 1. What is the product 2. What is the target market 3. What are the substitutes 4. How does the price and value for money are correlated 5. Is the product a luxury item 6. What sort of a decision sequence model can be usedHere is a brief answer to all of the questions mentioned above. As we all know that the product is a luxury SUV that is being marketed for the first time by the company, the company has to target to a specific group with specific characteristics. These people are supposed to be well to do by having good executive level jobs or running businesses and having a family of 2 to 3 persons. This suggests that the targeted customer should be more then 35 years of age but not more than 45 because that goes beyond the sporty and speedy characteristics of the car.The sport and speedy characteristics of the car open two marketing and targeting corridors for the company, that are, 1. executives and managing directors, (as discussed above) and 2. The existing sports cars clients who will then be filtered for having or not having a taste for a sports SUV. The problem is that the product that is in question in the research is quite expensive and thus it is not at all like marketing coke. Customers need to be educated and informed about the value and worth of the product that should be other than the actual cost price of the car (Bettman 1975).With reference to Blackwell, Miniard and Engel analytical framework, analyze the likely buying behavior of your target market, in terms of degree of problem solving, and identif y the probable influences on this decision process. You should also identify any issues related to the information processing aspect, as this will inform task 3 With reference to Blackwell, Miniard and Engel, the decision of any consumer is based upon and involves two or more products that are substitutes to each other.For example a consumer might choose between going out for a movie or staying at home, for this matter going to movie and staying at home will serve to be as substitutes to each other. Similarly, in this of Lamborghini, the consumers have a range of choices. These choices include other sporty SUV’s that already in the market by competitor brands like BMW, Mercedes, Chrysler and others. Thus Lamborghini should look into the matter that what do consumers want in an SUV, how and what characteristics they should highlight to attract their customers.Blackwell, Miniard and Engel advocate the fact that there are a number of cognitive processes going on in a consumer mi nd while he makes purchase decisions. These cognitive decisions can be identified as consumer knowledge about the market and the product, beliefs and memories about information that a consumer gathers from marketing and promotional activities going on around them, their cognitive process of comprehension and lastly their integration cognitive process in which a consumer evaluates two or more choices and short lists to one final choice.This choice is made on the basis of certain behavioral decisions, thus the decision making process of a consumer can also be regarded as their decision plan. A Cognitive Process Model of Consumer Decision Making Lamborghini should keep in mind that its consumers will gather most of the information from their surroundings. Apart from their own marketing campaign, the consumers consciously and unconsciously are gaining information about the sporty cars, their models, information about other brands, performance of other SUV’s that come I the same c ategory of sporty cars and much more.Consumers are exposed to TV shows, magazines, discussions and even get to see these products live at show rooms that they already a lot about the car. However, a marketer should always keep in mind that in order to attract a customer and give him what he wants, the product should be marketed in such a way that the consumer directly notices what he wants in the product without him being analyzing and comparing with other brands(Roberts 2000).The marketing campaign should highlight the characteristics of the product itself in the marketing campaign rather than letting the customer gather the information on his own that can also lead to possibilities that the customer may not be able to find those characteristics on his own. Same goes for Lamborghini, the company must market the new SUV in such a way that it highlights both its sporty nature and its symbol of power of status in order to cater both the target markets that have already been identified in the previous section.

Distinguish between cost leadership and differentiation strategies. Is Essay

Distinguish between cost leadership and differentiation strategies. Is it possible for a company or business unit to follow a cost leadership strategy and a differentiation strategy simultaneously - Essay Example Focus put on the cost leadership approach and differentiation strategy; this paper looks at the differences and the simultaneous working together of the two (Porter & Tanner 2012, pp. 12). Cost leadership strategy is the method by which a firm sets out becoming a low-cost producer in the industry. The cost advantages accrue from different sources depending on the structure of the industry. It may comprise the pursuit of economies of scale, preferential mobility to raw materials and the propriety technology. Low-cost producers tend to find and exploit all the sources of cost advantage. A firm that achieves and can sustain the overall cost leadership is above the average performer in the industry. Such company can command the prices near or at the industry standard (Porter & Tanner 2012, pp. 26). On the other hand, differentiation strategy is the method by which a firm seeks uniqueness in the industry. The distinctiveness is along some of the dimensions widely valued by the buyers. The procedure selects one or a number of attributes that majority of the customers in the industry perceive as significant. Companies in this category exceptionally position themselves to meet the identified needs of its clients. The exclusivity of this strategy is where the company rewarded with a premium price for its uniqueness (Porter & Tanner 2012, pp. 76) It is possible for the company to follow a cost leadership while it follows a differentiation strategy at the same time. Though it does not work for every company. A good example of an organization that can embrace the two approaches together is the Toyota corporation. The Toyota produces quality cars at low price accompanied by differentiating strategy. For example, the introduction of luxury brands of BMW cars and the Mercedes-Benz new series (Porter & Tanner 2012, pp. 138). Some scholars such as Porter argue that cost leadership and differentiation approaches are irreconcilable. A

Immunolocalization of the microtubule cytoskeleton Essay

Immunolocalization of the microtubule cytoskeleton - Essay Example The most prominent methods are: Western blot, spectrophotometry, enzyme assay, immunoprecipitation and immunostaining. In immunostaining, the method used during this procedure, an antibody is used to detect a specific protein epitope. These antibodies can be monoclonal or polyclonal. Then enzymes such as horseradish peroxidase or alkaline phosphatase are commonly used to catalyse reactions that give a coloured or chemiluminescent product. Fluorescent molecules can be visualised using fluoresence microscopy. During this experiment, the distribution of the protein tubulin in normal rat kidney (NRK) cells is explored. A monoclonal antibody that is specific for the -subunit of tubulin is used. Tubulin polymerizes into long, 25-nm wide microtubules that we will visualize with tubulin antibodies. The formation and maintenance of microtubules is cold sensitive. At 4C, microtubules are destabilized and they depolymerize. At 37C, human body temperature, they remain polymerized. Photograph 1 shows cells incubated at 4 0C, while photograph 2 shows cells incubated at 37 0C. At this stage of the procedure, microtubules cannot be detected in either of the photographs. 3 separate plates are used to create the NRK cells culture. ... The coverslip is then immersed in 3.7% formaldehyde (in PBS) at room temperature. Immersion in 0.2% Triton-X 100 (in PBS) detergent at room temperature follows. To prevent the subsequent antibody from sticking non-specifically to the cells on the coverslip, the coverslips should be incubated with cell-side-up with a 100-l droplet of 3% (w/v) bovine serum albumin (BSA). The incubation is done on a piece of Parafilm in a humid Petri dish for 15 minutes. An anti-tubulin dilution is prepared with 1 part antibody + 75 parts 1% (w/v) BSA in PBS. A 200 l total of antibody is necessary for the three coverslips. This tubulin antibody is a monoclonal antibody (12G10) and recognizes the -subunit of tubulin. Then each coverslip is overlayed each with a 100-l droplet of the diluted tubulin antibody. After that, a secondary antibody with 1 + 200 in 1% (w/v) BSA in PBS is used. The coverslips are placed back into the Petri dish chamber and overlay with a 100-l droplet of secondary antibody and they are incubate for 30 minutes at 37C. Therefore, we have 3 coverslips, all treated with the secondary antibody, 2 of them are treated with the primary antibody (one of them is incubated at 37C, and the other incubated at 4C) and 1 that is not treated with the primary antibody (incubated at 37C). The coverslips then are placed back into the Petri dish chamber and are overlaid for 30 minutes at 37C with a100-l droplet of Vectastain ABC reagent. This reagent contains a complex of avidin and the enzyme horseradish peroxidase (HRP). They are washed again with PBS. The drops of DAB (diaminobenzidine; a carcinogenic compound) are applied to the coverslips and incubate at room temperature for 5 minutes. After DAB incubation,